Sean Bugel, PhD
NIEHS Training Grant recipient (current)
GOAL: My overall goals are to use teleosts (e.g. zebrafish) as model vertebrates to understand the effects of environmental chemicals on vertebrate development and physiology.
FOCUS: My research focus is on elucidating the toxicity of chemicals relevant to human exposures and their potential impact on human health, as well as understanding the effects of contaminants pose a risk to aquatic species and ecosystem health.
EXPERIENCE: My previous experience is with reproductive endocrine disruption of oogenesis in teleosts and reproductive dysfunction caused by cross-talk between the aryl hydrocarbon and the estrogen receptor pathways. Currently, I am involved in developmental toxicity of phytoestrogens, development of a high throughput endocrine disruption screen, endocrine disrupting effects of bisphenol A, and development of estrogen receptor knock out zebrafish.