TitleWorkflow for Comparison of Chemical and Biological Metrics of Filter Collected PM.
Publication TypeJournal Article
Year of Publication2020
AuthorsRoper, C, Perez, A, Barrett, D, Hystad, P, Simonich, SLMassey, Tanguay, RL
JournalAtmos Environ (1994)
Volume226
Date Published2020 Apr 01
ISSN1352-2310
Abstract

There is limited understanding of adverse health effect associations with chemical constituents of fine particulate matter (PM) as well as the underlying mechanisms. We outlined a workflow to assess metrics, beyond concentration, using household and personal PM filter samples collected in India as a proof of concept for future large-scale studies. Oxidative potential, chemical composition (polycyclic aromatic hydrocarbons and elements), and bioactivity (developmental exposures in zebrafish) were determined. Significant differences were observed in all metrics between personal and household PM samples. This work established methods to characterize multiple metrics of PM to ultimately support the identification of more health-relevant metrics than concentration.

DOI10.1016/j.atmosenv.2020.117379
Alternate JournalAtmos Environ (1994)
PubMed ID32313426
PubMed Central IDPMC7170255
Grant ListP42 ES016465 / ES / NIEHS NIH HHS / United States
T32 ES007060 / ES / NIEHS NIH HHS / United States